plathlab

Using molecular dynamics simulations to prioritize and understand AI-generated

Embryonal rhabdomyosarcoma of the uterine corpus: a clinicopathological and molecular evaluation of 21 circumstances highlighting a frequent affiliation with DICER1 mutations
Herein we evaluated a sequence of 21 embryonal rhabdomyosarcomas of the uterine corpus (ucERMS), a uncommon neoplasm, to characterize their morphology, genomics, and habits. Sufferers ranged from 27 to 73 (median 52) years and tumors from Four to 15 (median 9) cm, with extrauterine illness famous in two.
Comply with-up (median 16 months) was accessible for 14/21 sufferers; 9 had been alive and properly, 4 died of illness, and one died from different causes. Most tumors (16/21) confirmed predominantly basic morphology, comprised of alternating hyper- and hypocellular areas of primitive small cells and differentiating rhabdomyoblasts in a free myxoid/edematous stroma.
A cambium layer was famous in all; seven had heterologous components (six with fetal-type cartilage) and eight displayed focal anaplasia. The remaining 5 neoplasms confirmed solely a minor part (≤20%) of basic morphology, with anaplasia famous in 4 and tumor cell necrosis in three. Probably the most frequent mutations detected had been in DICER1 (14/21), TP53 (7/20), PI3K/AKT/mTOR pathway (7/20), and KRAS/NRAS (5/20). Copy-number alterations had been current in 10/19 tumors.
Total, 8/14 DICER1-associated ucERMS confirmed concurrent lack of operate and hotspot mutations in DICER1, which is a characteristic extra more likely to be seen in tumors related to DICER1 syndrome.
Germline information had been accessible for 2 sufferers, each DICER1 wild sort (one with concurrent lack of operate and hotspot alterations). DICER1-associated ucERMS had been extra more likely to present a basic histological look together with heterologous components than DICER1-independent tumors.
No variations in survival had been famous between the 2 teams, however each sufferers with extrauterine illness at prognosis and two with recurrences died from illness. As no sufferers had a recognized private or household historical past of DICER1 syndrome, we favor most DICER1-associated ucERMS to be sporadic.

Utilizing molecular dynamics simulations to prioritize and perceive AI-generated cell penetrating peptides

Cell-penetrating peptides have necessary therapeutic purposes in drug supply, however the number of recognized cell-penetrating peptides continues to be restricted. With a promise to speed up peptide improvement, synthetic intelligence (AI) strategies together with deep generative fashions are at present in highlight.
Scientists, nevertheless, are sometimes overwhelmed by an extreme variety of unannotated sequences generated by AI and discover it troublesome to acquire insights to prioritize them for experimental validation. To keep away from this pitfall, we leverage molecular dynamics (MD) simulations to acquire mechanistic info to prioritize and perceive AI-generated peptides.
A mechanistic rating of permeability is computed from 5 steered MD simulations ranging from totally different preliminary constructions predicted by homology modelling. To compensate for variability of predicted constructions, the rating is computed with pattern variance penalization so {that a} peptide with constant behaviour is extremely evaluated.
Our computational pipeline involving deep studying, homology modelling, MD simulations and synthesizability evaluation generated 24 novel peptide sequences. The highest-scoring peptide confirmed a constant sample of conformational change in all simulations no matter preliminary constructions.
Because of wet-lab-experiments, our peptide confirmed higher permeability and weaker toxicity compared to a clinically used peptide, TAT. Our consequence demonstrates how MD simulations can help de novo peptide design by offering mechanistic info supplementing statistical inference.
plathlab
plathlab

TNF Alpha Monoclonal Antibody
ABM40205-01ml 0.1ml
EUR 346.8
Description: A monoclonal antibody for detection of TNF Alpha from Human, Mouse, Rat. This TNF Alpha antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

TNF Alpha Monoclonal Antibody
ABM40205-02ml 0.2ml
EUR 496.8
Description: A monoclonal antibody for detection of TNF Alpha from Human, Mouse, Rat. This TNF Alpha antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

TNF Alpha Monoclonal Antibody
ABM40206-003ml 0.03ml
EUR 189.6
Description: A monoclonal antibody for detection of TNF Alpha from Human, Mouse, Rat. This TNF Alpha antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

TNF Alpha Monoclonal Antibody
ABM40206-01ml 0.1ml
EUR 346.8
Description: A monoclonal antibody for detection of TNF Alpha from Human, Mouse, Rat. This TNF Alpha antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

TNF Alpha Monoclonal Antibody
ABM40206-02ml 0.2ml
EUR 496.8
Description: A monoclonal antibody for detection of TNF Alpha from Human, Mouse, Rat. This TNF Alpha antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Monoclonal TNF Alpha Antibody (clone 2C8), Clone: 2C8
APR10497G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human TNF Alpha (clone 2C8). The antibodies are raised in Mouse and are from clone 2C8. This antibody is applicable in IHC-P

Mouse anti Rat TNF monoclonal antibody
CABT-L378 100ug
EUR 858

α-SMA Monoclonal Antibody
40482-100ul 100ul
EUR 302.4

α-SMA Monoclonal Antibody
40482-50ul 50ul
EUR 224.4

α-SMA Monoclonal Antibody
40495-100ul 100ul
EUR 302.4

α-SMA Monoclonal Antibody
40495-50ul 50ul
EUR 224.4

Mouse anti Canine TNF monoclonal antibody
CABT-L129 500ug
EUR 982.8

Mouse anti Porcine TNF monoclonal antibody
CABT-L382 500ug
EUR 1008

Mouse anti Porcine TNF monoclonal antibody
CABT-L383 250 ug
EUR 1070.4

TNF Receptor II recombinant monoclonal antibody
A5046 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human TNF Receptor II for WB,ELISA

Mouse anti Guinea Pig TNF monoclonal antibody
CABT-L155 500ug
EUR 982.8

Mouse anti Guinea Pig TNF monoclonal antibody
CABT-L156 250ug
EUR 1057.2

HSP90 α Monoclonal antibody(1F6)
44076-100ul 100ul
EUR 302.4

HSP90 α Monoclonal antibody(7D6)
44078-100ul 100ul
EUR 302.4

Rat anti Rhesus Macaque TNF monoclonal antibody
CABT-L376 500ug
EUR 982.8

Monoclonal TNF alpha Antibody, Clone: EP1085Y
APR10496G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human TNF alpha. The antibodies are raised in Rabbit and are from clone EP1085Y. This antibody is applicable in WB

Monoclonal TNF-alpha Antibody, Clone: 2A9B9
APR13767G 0.1ml
EUR 580.8
Description: A Monoclonal antibody against Human TNF-alpha. The antibodies are raised in Mouse and are from clone 2A9B9. This antibody is applicable in WB, E

α-tubulin Mouse Monoclonal Antibody
37981-100ul 100ul
EUR 302.4

α-tubulin Mouse Monoclonal Antibody
37981-50ul 50ul
EUR 224.4

Monoclonal FH Antibody (monoclonal) (M07), Clone: 5C12
AMM04543G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FH (monoclonal) (M07). The antibodies are raised in mouse and are from clone 5C12. This antibody is applicable in WB and IF, E

Monoclonal TAZ Antibody (monoclonal) (M19), Clone: 3C10
APR10350G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human TAZ (monoclonal) (M19). The antibodies are raised in mouse and are from clone 3C10. This antibody is applicable in IF, E

Monoclonal RP2 Antibody (monoclonal) (M02), Clone: 5C10
APR13143G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RP2 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 5C10. This antibody is applicable in WB, E

Monoclonal ID2 Antibody (monoclonal) (M04), Clone: 2C11
APR16801G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ID2 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 2C11. This antibody is applicable in WB

Monoclonal ENG Antibody (monoclonal) (M01), Clone: 4C11
AMM03494G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ENG (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C11. This antibody is applicable in WB, IP, E

PTEN (2C10) Monoclonal Antibody
EM1308-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against PTEN (2C10) from Human. This antibody is tested and validated for IHC

PTEN (2C10) Monoclonal Antibody
EM1308-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against PTEN (2C10) from Human. This antibody is tested and validated for IHC

Monoclonal NCF4 Antibody (monoclonal) (M01), Clone: 3C10
APR08620G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human NCF4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C10. This antibody is applicable in E

Monoclonal PER2 Antibody (monoclonal) (M01), Clone: 5C10
APR09041G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human PER2 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 5C10. This antibody is applicable in WB, IHC and IF, E

Monoclonal VAPA Antibody (monoclonal) (M01), Clone: 4C12
APR10689G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human VAPA (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C12. This antibody is applicable in WB and IF

Monoclonal SOX9 Antibody (monoclonal) (M02), Clone: 3C10
APR13498G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SOX9 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 3C10. This antibody is applicable in WB, IHC and IF, IP

Monoclonal ENC1 Antibody (monoclonal) (M03), Clone: 3C10
APR11826G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ENC1 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 3C10. This antibody is applicable in WB

Monoclonal SGCB Antibody (monoclonal) (M02), Clone: 1C10
AMM07766G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human SGCB (monoclonal) (M02). The antibodies are raised in mouse and are from clone 1C10. This antibody is applicable in WB, IHC and IF, E

Monoclonal FUT7 Antibody (monoclonal) (M03), Clone: 1C12
AMM03560G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FUT7 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 1C12. This antibody is applicable in WB, E

Monoclonal GLMN Antibody (monoclonal) (M01), Clone: 1C12
AMM03583G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GLMN (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C12. This antibody is applicable in WB and IF, IP

Monoclonal ICT1 Antibody (monoclonal) (M06), Clone: 4C10
AMM03646G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ICT1 (monoclonal) (M06). The antibodies are raised in mouse and are from clone 4C10. This antibody is applicable in E

Monoclonal IL10 Antibody (monoclonal) (M03), Clone: 1C10
AMM03660G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human IL10 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 1C10. This antibody is applicable in WB

Monoclonal MID1 Antibody (monoclonal) (M06), Clone: 2C11
AMM03797G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MID1 (monoclonal) (M06). The antibodies are raised in mouse and are from clone 2C11. This antibody is applicable in WB

Monoclonal MRC1 Antibody (monoclonal) (M02), Clone: 5C11
AMM03811G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MRC1 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 5C11. This antibody is applicable in WB and IHC, E

Monoclonal RHOA Antibody (monoclonal) (M06), Clone: 1C10
AMM04010G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RHOA (monoclonal) (M06). The antibodies are raised in mouse and are from clone 1C10. This antibody is applicable in WB and IF

Monoclonal TOE1 Antibody (monoclonal) (M02), Clone: 1C12
AMM04226G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human TOE1 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 1C12. This antibody is applicable in WB, IHC and IF

Monoclonal ETV5 Antibody (monoclonal) (M02), Clone: 7C10
AMM04466G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ETV5 (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 7C10. This antibody is applicable in WB, E

Monoclonal FUT2 Antibody (monoclonal) (M02), Clone: 4C12
AMM04650G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FUT2 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 4C12. This antibody is applicable in WB

Monoclonal GALT Antibody (monoclonal) (M01), Clone: 4C11
AMM04684G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GALT (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C11. This antibody is applicable in WB and IHC, E

Monoclonal GYG1 Antibody (monoclonal) (M08), Clone: 2C10
AMM05277G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GYG1 (monoclonal) (M08). The antibodies are raised in mouse and are from clone 2C10. This antibody is applicable in WB

Monoclonal ULK2 Antibody (monoclonal) (M01), Clone: 6C12
AMM08424G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ULK2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 6C12. This antibody is applicable in WB, E

Monoclonal SAA1 Antibody (monoclonal) (M01), Clone: 3C11-2C1
AMM04067G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SAA1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C11-2C1. This antibody is applicable in WB and IHC

Monoclonal GPD1 Antibody (monoclonal) (M01), Clone: 3C10-1C4
AMM05179G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GPD1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C10-1C4. This antibody is applicable in WB, E

Monoclonal ZYX Antibody (monoclonal) (M01), Clone: 2C10-4A7
APR14058G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ZYX (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C10-4A7. This antibody is applicable in WB and IF, IP, E

Monoclonal SMAD3 Antibody (monoclonal) (M09), Clone: 1C11
APR10163G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SMAD3 (monoclonal) (M09). The antibodies are raised in mouse and are from clone 1C11. This antibody is applicable in WB and IF, E

Monoclonal SDCBP Antibody (monoclonal) (M01), Clone: 2C12
APR13235G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SDCBP (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12. This antibody is applicable in WB, IHC and IF, IP

Monoclonal STAU1 Antibody (monoclonal) (M03), Clone: 3C12
APR13570G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human STAU1 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 3C12. This antibody is applicable in WB and IF, E

Monoclonal MAPK9 Antibody (monoclonal) (M03), Clone: 3C12
APR08334G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MAPK9 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 3C12. This antibody is applicable in WB and IF, E

Monoclonal MTHFS Antibody (monoclonal) (M01), Clone: 2C12
APR08551G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MTHFS (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12. This antibody is applicable in WB

Monoclonal GAP43 Antibody (monoclonal) (M01), Clone: 3C11
APR11999G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GAP43 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C11. This antibody is applicable in WB, E

Monoclonal AKAP4 Antibody (monoclonal) (M02), Clone: 4C10
APR14896G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human AKAP4 (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 4C10. This antibody is applicable in WB and IHC, E

Monoclonal BARX1 Antibody (monoclonal) (M05), Clone: 3C11
APR15115G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human BARX1 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 3C11. This antibody is applicable in WB and IF, E

Monoclonal CETN1 Antibody (monoclonal) (M05), Clone: 4C12
APR15413G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CETN1 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 4C12. This antibody is applicable in WB

Monoclonal FKBP4 Antibody (monoclonal) (M01), Clone: 5C11
APR15990G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FKBP4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5C11. This antibody is applicable in WB and IHC, IP, E

Monoclonal ITGA4 Antibody (monoclonal) (M01), Clone: 2C11
APR16914G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ITGA4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C11. This antibody is applicable in WB, E

Monoclonal MAPK6 Antibody (monoclonal) (M02), Clone: 4C11
APR17302G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human MAPK6 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 4C11. This antibody is applicable in WB and IF

Monoclonal OXSR1 Antibody (monoclonal) (M18), Clone: 4C12
APR17697G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human OXSR1 (monoclonal) (M18). The antibodies are raised in mouse and are from clone 4C12. This antibody is applicable in WB and IF, E

Monoclonal PDE3A Antibody (monoclonal) (M01), Clone: 5C12
AMM07052G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PDE3A (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5C12. This antibody is applicable in WB, E

Monoclonal PPIL4 Antibody (monoclonal) (M01), Clone: 1C10
AMM07288G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PPIL4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C10. This antibody is applicable in WB and IF

Monoclonal RAB43 Antibody (monoclonal) (M09), Clone: 4C11
AMM07480G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RAB43 (monoclonal) (M09). The antibodies are raised in mouse and are from clone 4C11. This antibody is applicable in WB, E

Monoclonal RAMP3 Antibody (monoclonal) (M01), Clone: 1C11
AMM07513G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RAMP3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C11. This antibody is applicable in WB, E

Monoclonal SCAP1 Antibody (monoclonal) (M02), Clone: 1C11
AMM07727G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SCAP1 (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 1C11. This antibody is applicable in WB, E

Monoclonal SNX12 Antibody (monoclonal) (M01), Clone: 2C10
AMM07906G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SNX12 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C10. This antibody is applicable in WB, E

Monoclonal FBXO8 Antibody (monoclonal) (M01), Clone: 1C11
AMM03533G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FBXO8 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C11. This antibody is applicable in WB, E

Monoclonal GSDML Antibody (monoclonal) (M06), Clone: 4C10
AMM03598G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GSDML (monoclonal) (M06). The antibodies are raised in mouse and are from clone 4C10. This antibody is applicable in WB, E

Monoclonal HDAC1 Antibody (monoclonal) (M14), Clone: 5C11
AMM03610G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human HDAC1 (monoclonal) (M14). The antibodies are raised in mouse and are from clone 5C11. This antibody is applicable in WB, IHC and IF, E

Monoclonal MMP28 Antibody (monoclonal) (M01), Clone: 3C11
AMM03804G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MMP28 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C11. This antibody is applicable in WB, E

Monoclonal MS4A1 Antibody (monoclonal) (M01), Clone: 5C11
AMM03813G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MS4A1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5C11. This antibody is applicable in WB, E

Monoclonal OTUB1 Antibody (monoclonal) (M09), Clone: 1C12
AMM03874G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human OTUB1 (monoclonal) (M09). The antibodies are raised in Mouse and are from clone 1C12. This antibody is applicable in WB, E

Monoclonal PCGF2 Antibody (monoclonal) (M04), Clone: 4C10
AMM03895G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PCGF2 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 4C10. This antibody is applicable in WB

Monoclonal PRDX4 Antibody (monoclonal) (M01), Clone: 2C12
AMM03935G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human PRDX4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12. This antibody is applicable in WB and IHC

Monoclonal RAB4A Antibody (monoclonal) (M01), Clone: 1C10
AMM03978G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RAB4A (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 1C10. This antibody is applicable in WB, E

Monoclonal RASA1 Antibody (monoclonal) (M01), Clone: 2C12
AMM03992G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RASA1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12. This antibody is applicable in WB and IHC, E

Monoclonal RUNX1 Antibody (monoclonal) (M06), Clone: 2C10
AMM04049G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RUNX1 (monoclonal) (M06). The antibodies are raised in mouse and are from clone 2C10. This antibody is applicable in WB, IHC and IF, E

Monoclonal SNAI2 Antibody (monoclonal) (M05), Clone: 3C12
AMM04119G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SNAI2 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 3C12. This antibody is applicable in WB and IF

Monoclonal TBX18 Antibody (monoclonal) (M04), Clone: 3C12
AMM04168G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human TBX18 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 3C12. This antibody is applicable in WB

Monoclonal TGIF2 Antibody (monoclonal) (M01), Clone: 4C10
AMM04194G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human TGIF2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C10. This antibody is applicable in WB, E

Monoclonal USP15 Antibody (monoclonal) (M01), Clone: 1C10
AMM04295G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human USP15 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C10. This antibody is applicable in WB and IF

Monoclonal FOXA2 Antibody (monoclonal) (M12), Clone: 6C12
AMM04593G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FOXA2 (monoclonal) (M12). The antibodies are raised in Mouse and are from clone 6C12. This antibody is applicable in WB, IHC and IF, E

Monoclonal CNAP1 Antibody (monoclonal) (M01), Clone: 4C12
AMM03400G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CNAP1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C12. This antibody is applicable in WB, IHC and IF, E

Monoclonal CSE1L Antibody (monoclonal) (M03), Clone: 2C10
AMM03419G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CSE1L (monoclonal) (M03). The antibodies are raised in mouse and are from clone 2C10. This antibody is applicable in WB, IHC and IF, E

Monoclonal CLCA1 Antibody (monoclonal) (M03), Clone: 2C10
APG02621G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CLCA1 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 2C10. This antibody is applicable in WB, E

Monoclonal CSPG5 Antibody (monoclonal) (M01), Clone: 5C11
APG03231G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CSPG5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5C11. This antibody is applicable in WB, E

Monoclonal PSMC2 Antibody (monoclonal) (M01), Clone: 4C10-2C8
AMM03955G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PSMC2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C10-2C8. This antibody is applicable in WB and IF, E

Monoclonal GNG7 Antibody (monoclonal) (M01), Clone: 1C11-1B3
AMM04835G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GNG7 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C11-1B3. This antibody is applicable in WB, E

Monoclonal GPD2 Antibody (monoclonal) (M02), Clone: 2C11-1F4
AMRa00041G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GPD2 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 2C11-1F4. This antibody is applicable in WB, E

Monoclonal MAPK13 Antibody (monoclonal) (M01), Clone: 2C10-1C7
AMM03770G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MAPK13 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C10-1C7. This antibody is applicable in WB and IF

Monoclonal SREBF1 Antibody (monoclonal) (M02), Clone: 4C11
APR10239G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SREBF1 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 4C11. This antibody is applicable in WB, E

Monoclonal SQSTM1 Antibody (monoclonal) (M01), Clone: 2C11
APR07188G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SQSTM1 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 2C11. This antibody is applicable in WB and IF, E

Monoclonal AKAP10 Antibody (monoclonal) (M04), Clone: 8C10
APR14894G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human AKAP10 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 8C10. This antibody is applicable in WB and IHC, E

Monoclonal ANXA10 Antibody (monoclonal) (M02), Clone: 1C12
APR14944G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ANXA10 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 1C12. This antibody is applicable in E

Monoclonal KIF26A Antibody (monoclonal) (M01), Clone: 3C10
APR17003G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human KIF26A (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C10. This antibody is applicable in WB, E

Monoclonal PGRMC2 Antibody (monoclonal) (M04), Clone: 3C11
AMM07133G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PGRMC2 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 3C11. This antibody is applicable in WB and IHC, E

Monoclonal FBXO11 Antibody (monoclonal) (M01), Clone: 4C12
AMM03527G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FBXO11 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C12. This antibody is applicable in WB, IHC and IF, E

Monoclonal ISGF3G Antibody (monoclonal) (M01), Clone: 1C10
AMM03694G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ISGF3G (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C10. This antibody is applicable in WB and IHC, E

Monoclonal CAPN5 Antibody (monoclonal) (M02A), Clone: 3C10
AMM03318G 0.1ml
EUR 580.8
Description: A Monoclonal antibody against Human CAPN5 (monoclonal) (M02A). The antibodies are raised in Mouse and are from clone 3C10. This antibody is applicable in WB

Monoclonal CDC14A Antibody (monoclonal) (M01), Clone: 2C12
AMM03354G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CDC14A (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12. This antibody is applicable in WB and IF, E

Monoclonal KCNJ10 Antibody (monoclonal) (M01), Clone: 1C11
AMM06100G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human KCNJ10 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C11. This antibody is applicable in WB, E

Monoclonal AKR1C2 Antibody (monoclonal) (M03), Clone: 3C11
APG01662G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human AKR1C2 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 3C11. This antibody is applicable in WB, E

Monoclonal AKR1C4 Antibody (monoclonal) (M01), Clone: 2C11
APG01666G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human AKR1C4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C11. This antibody is applicable in WB, IHC and IF, E

Monoclonal CAMK2A Antibody (monoclonal) (M03), Clone: 2C12
APG02356G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CAMK2A (monoclonal) (M03). The antibodies are raised in mouse and are from clone 2C12. This antibody is applicable in WB and IF, E

Monoclonal PCDHGA8 Antibody (monoclonal) (M01), Clone: 1C11
APR12783G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PCDHGA8 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C11. This antibody is applicable in WB, E

Monoclonal PPP2R2B Antibody (monoclonal) (M01), Clone: 2C11
APR12944G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PPP2R2B (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C11. This antibody is applicable in WB

Monoclonal CTNNAL1 Antibody (monoclonal) (M05), Clone: 2C11
APR15626G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CTNNAL1 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 2C11. This antibody is applicable in E

Monoclonal RAPGEF4 Antibody (monoclonal) (M01), Clone: 1C11
AMM07530G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RAPGEF4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C11. This antibody is applicable in WB, E

Monoclonal FCER1A Antibody (monoclonal) (M01), Clone: 2C12-3B6
AMM03535G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human FCER1A (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12-3B6. This antibody is applicable in WB, E

Monoclonal ALDOA Antibody (monoclonal) (M02), Clone: 3C12-6D11
APG01799G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ALDOA (monoclonal) (M02). The antibodies are raised in mouse and are from clone 3C12-6D11. This antibody is applicable in WB and IF

Monoclonal APEG1 Antibody (monoclonal) (M01), Clone: 2C2-2C7
AMM03267G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human APEG1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C2-2C7. This antibody is applicable in WB, E

Monoclonal CCL11 Antibody (monoclonal) (M01), Clone: 1C8-2C1
AMM03328G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CCL11 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C8-2C1. This antibody is applicable in WB

Monoclonal PAFAH1B3 Antibody (monoclonal) (M02), Clone: 8C11
APR08918G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PAFAH1B3 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 8C11. This antibody is applicable in WB and IF, E

Monoclonal SLC2A4RG Antibody (monoclonal) (M02), Clone: 4C10
APR10069G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SLC2A4RG (monoclonal) (M02). The antibodies are raised in mouse and are from clone 4C10. This antibody is applicable in WB and IF

Monoclonal PAFAH1B1 Antibody (monoclonal) (M01), Clone: 2C12
APR12703G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PAFAH1B1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12. This antibody is applicable in WB, E

Monoclonal MGC40579 Antibody (monoclonal) (M11), Clone: 2C11
APR08430G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MGC40579 (monoclonal) (M11). The antibodies are raised in mouse and are from clone 2C11. This antibody is applicable in WB, E

Monoclonal IL1RAPL1 Antibody (monoclonal) (M04), Clone: 1C10
APG03381G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human IL1RAPL1 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 1C10. This antibody is applicable in WB, E

Monoclonal STAT4 Antibody (monoclonal) (M01), Clone: 1C2-1C12
AMM04144G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human STAT4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C2-1C12. This antibody is applicable in WB, IHC and IF, IP, E

Monoclonal HBZ Antibody (monoclonal) (M01), Clone: 3C4-1D5
AMM03604G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human HBZ (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C4-1D5. This antibody is applicable in WB, E

Monoclonal VCL Antibody (monoclonal) (M01), Clone: 2C6-1B5
AMM04309G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human VCL (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C6-1B5. This antibody is applicable in WB and IF

Monoclonal C10orf4 Antibody (monoclonal) (M02), Clone: 2C4
AMM03293G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human C10orf4 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 2C4. This antibody is applicable in WB

Monoclonal DNAJB6 Antibody (monoclonal) (M01), Clone: 2C11-C1
APR11766G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human DNAJB6 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 2C11-C1. This antibody is applicable in WB and IF, E

Monoclonal MASA Antibody (monoclonal) (M01), Clone: 3C1-1D5
APR08335G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MASA (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C1-1D5. This antibody is applicable in WB

Monoclonal XPO5 Antibody (monoclonal) (M01), Clone: 2C5-1B3
AMM08531G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human XPO5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C5-1B3. This antibody is applicable in WB and IF, IP, E

Monoclonal F9 Antibody (monoclonal) (M01), Clone: 2C9
AMM03511G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human F9 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C9. This antibody is applicable in WB, IP, E

Monoclonal T Antibody (monoclonal) (M02), Clone: 5C5
AMM04164G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human T (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 5C5. This antibody is applicable in WB, E

Monoclonal KIAA0101 Antibody (monoclonal) (M01), Clone: 3C11-1F11
APR08093G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human KIAA0101 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C11-1F11. This antibody is applicable in WB, IHC and IF, E

Monoclonal THAP1 Antibody (monoclonal) (M01), Clone: 2C1-2F2
APR10467G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human THAP1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C1-2F2. This antibody is applicable in WB and IF

Monoclonal ENPP5 Antibody (monoclonal) (M01), Clone: 1C5-1D7
APR11831G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ENPP5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C5-1D7. This antibody is applicable in WB

Monoclonal BAMBI Antibody (monoclonal) (M01), Clone: 3C1-1D1
APR15107G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human BAMBI (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 3C1-1D1. This antibody is applicable in WB, E

Monoclonal G22P1 Antibody (monoclonal) (M01), Clone: 4C2-1A6
AMM03567G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human G22P1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C2-1A6. This antibody is applicable in WB, IHC and IF, E

Monoclonal MPP1 Antibody (monoclonal) (M02), Clone: 1C3-1D11
AMM03809G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MPP1 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 1C3-1D11. This antibody is applicable in WB, E

Monoclonal UBE2H Antibody (monoclonal) (M01), Clone: 3C4-1A2
AMM04278G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human UBE2H (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C4-1A2. This antibody is applicable in WB and IF, E

17-α-hydoxy progesterone monoclonal antibody
10R-11483 1 mg
EUR 891.6
Description: Mouse anti-17-α-hydoxy progesterone monoclonal antibody

Monoclonal PDZK1 Antibody (monoclonal) (M01), Clone: 1C3-2B11
APR09031G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human PDZK1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C3-2B11. This antibody is applicable in WB and IHC, E

Monoclonal HSPE1 Antibody (monoclonal) (M01), Clone: 4C11-B11
APR07842G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human HSPE1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C11-B11. This antibody is applicable in WB and IF, E

Monoclonal HDAC11 Antibody (monoclonal) (M01), Clone: 1C2-2G5
APR16678G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human HDAC11 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C2-2G5. This antibody is applicable in WB and IF, E

Monoclonal GENX-3414 Antibody (monoclonal) (M11), Clone: 2C10
AMM03581G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GENX-3414 (monoclonal) (M11). The antibodies are raised in mouse and are from clone 2C10. This antibody is applicable in WB

Monoclonal UBE2D3 Antibody (monoclonal) (M01), Clone: 4C1-1E3
AMM04274G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human UBE2D3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4C1-1E3. This antibody is applicable in WB, E

GSK3? (2C6) Monoclonal Antibody
EM1283-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against GSK3? (2C6) from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

GSK3? (2C6) Monoclonal Antibody
EM1283-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against GSK3? (2C6) from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

NBR1 (7C3) Monoclonal Antibody
EM1373-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against NBR1 (7C3) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC

NBR1 (7C3) Monoclonal Antibody
EM1373-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against NBR1 (7C3) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC

ATG5 (3C7) Monoclonal Antibody
EM1374-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against ATG5 (3C7) from Human/ Mouse/ Rat. This antibody is tested and validated for WB, ELISA, IHC

ATG5 (3C7) Monoclonal Antibody
EM1374-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against ATG5 (3C7) from Human/ Mouse/ Rat. This antibody is tested and validated for WB, ELISA, IHC

Monoclonal ARHGDIB Antibody (monoclonal) (M01), Clone: 2C12-B6
APR15024G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ARHGDIB (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C12-B6. This antibody is applicable in E

Smad3 (4C9) Monoclonal Antibody
EM1315-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against Smad3 (4C9) from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

Smad3 (4C9) Monoclonal Antibody
EM1315-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against Smad3 (4C9) from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

Monoclonal T Antibody, Clone: 6C12
AMM02901G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human T. The antibodies are raised in Mouse and are from clone 6C12. This antibody is applicable in WB, FC, E

Monoclonal SP1 Antibody (monoclonal) (M03), Clone: 4C8
APR10214G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SP1 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 4C8. This antibody is applicable in WB, IHC and IF, E

Monoclonal SFN Antibody (monoclonal) (M01), Clone: 3C3
APR13282G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SFN (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 3C3. This antibody is applicable in WB and IHC, IP

Monoclonal YY1 Antibody (monoclonal) (M01), Clone: 2C4
APR14013G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human YY1 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 2C4. This antibody is applicable in WB, IHC and IF, E

Monoclonal YY1 Antibody (monoclonal) (M04), Clone: 2C5
APR14016G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human YY1 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 2C5. This antibody is applicable in WB, IHC and IF, E

Monoclonal YY1 Antibody (monoclonal) (M05), Clone: 4C1
APR14017G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human YY1 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 4C1. This antibody is applicable in WB and IF, E

Monoclonal DLD Antibody (monoclonal) (M02), Clone: 3C1
APR07594G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human DLD (monoclonal) (M02). The antibodies are raised in mouse and are from clone 3C1. This antibody is applicable in WB and IHC, E

Monoclonal IL6 Antibody (monoclonal) (M08), Clone: 2C5
APR07988G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human IL6 (monoclonal) (M08). The antibodies are raised in mouse and are from clone 2C5. This antibody is applicable in WB

Monoclonal ID2 Antibody (monoclonal) (M01), Clone: 3C3
APR16800G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ID2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C3. This antibody is applicable in WB, E

Monoclonal HN1 Antibody (monoclonal) (M01), Clone: 2C8
AMM03628G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human HN1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C8. This antibody is applicable in WB

Monoclonal NOV Antibody (monoclonal) (M01), Clone: 3C2
AMM03865G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human NOV (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C2. This antibody is applicable in WB, E

Monoclonal PGR Antibody (monoclonal) (M04), Clone: 2C2
AMM03911G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PGR (monoclonal) (M04). The antibodies are raised in mouse and are from clone 2C2. This antibody is applicable in WB, IHC and IF, E

Monoclonal PTN Antibody (monoclonal) (M01), Clone: 5C3
AMM03968G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PTN (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 5C3. This antibody is applicable in WB and IHC

Monoclonal SRF Antibody (monoclonal) (M02), Clone: 1C8
AMM04134G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SRF (monoclonal) (M02). The antibodies are raised in mouse and are from clone 1C8. This antibody is applicable in WB, E

Monoclonal TEK Antibody (monoclonal) (M06), Clone: 3C1
AMM04186G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human TEK (monoclonal) (M06). The antibodies are raised in mouse and are from clone 3C1. This antibody is applicable in WB, E

Monoclonal GLS Antibody (monoclonal) (M01), Clone: 5C4
AMM04796G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GLS (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 5C4. This antibody is applicable in WB and IF, E

Monoclonal CNO Antibody (monoclonal) (M02), Clone: 6C3
AMM03402G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CNO (monoclonal) (M02). The antibodies are raised in mouse and are from clone 6C3. This antibody is applicable in WB, IHC and IF, E

GRP78/Bip Monoclonal Antibody(10C9)
44087-100ul 100ul
EUR 302.4

P38 Mouse Monoclonal Antibody(8C11)
44250-100ul 100ul
EUR 302.4

P38 Mouse Monoclonal Antibody (8C11)
ABM40363-003ml 0.03ml
EUR 189.6
Description: A monoclonal antibody for detection of P38 from Human, Mouse, Rat. This P38 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of P38

P38 Mouse Monoclonal Antibody (8C11)
ABM40363-01ml 0.1ml
EUR 346.8
Description: A monoclonal antibody for detection of P38 from Human, Mouse, Rat. This P38 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of P38

P38 Mouse Monoclonal Antibody (8C11)
ABM40363-02ml 0.2ml
EUR 496.8
Description: A monoclonal antibody for detection of P38 from Human, Mouse, Rat. This P38 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of P38

Monoclonal OLR1 Antibody (monoclonal) (M08), Clone: 2C9
APR08858G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human OLR1 (monoclonal) (M08). The antibodies are raised in mouse and are from clone 2C9. This antibody is applicable in E

Monoclonal SOD3 Antibody (monoclonal) (M01), Clone: 5C3
APR10201G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human SOD3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5C3. This antibody is applicable in WB, E

Monoclonal TDO2 Antibody (monoclonal) (M01), Clone: 1C8
APR10391G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human TDO2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C8. This antibody is applicable in E

Monoclonal PALM Antibody (monoclonal) (M09), Clone: 7C5
APR12711G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PALM (monoclonal) (M09). The antibodies are raised in mouse and are from clone 7C5. This antibody is applicable in WB and IHC, E

Monoclonal RFNG Antibody (monoclonal) (M08), Clone: 6C7
APR13088G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human RFNG (monoclonal) (M08). The antibodies are raised in mouse and are from clone 6C7. This antibody is applicable in WB and IF

Monoclonal SNCG Antibody (monoclonal) (M01), Clone: 2C3
APR13439G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human SNCG (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C3. This antibody is applicable in WB

Monoclonal SOX4 Antibody (monoclonal) (M01), Clone: 2C5
APR13473G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human SOX4 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C5. This antibody is applicable in E

Monoclonal STAC Antibody (monoclonal) (M01), Clone: 2C5
APR13561G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human STAC (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C5. This antibody is applicable in WB, E

Monoclonal ZIC4 Antibody (monoclonal) (M07), Clone: 2C2
APR14046G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ZIC4 (monoclonal) (M07). The antibodies are raised in mouse and are from clone 2C2. This antibody is applicable in WB and IF, E

Monoclonal ENO1 Antibody (monoclonal) (M03), Clone: 3C8
APR07683G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ENO1 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 3C8. This antibody is applicable in WB

Monoclonal MFN1 Antibody (monoclonal) (M04), Clone: 3C9
APR08439G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human MFN1 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 3C9. This antibody is applicable in WB, E

Monoclonal CNR2 Antibody (monoclonal) (M01), Clone: 3C7
APR11612G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CNR2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3C7. This antibody is applicable in WB and IF, E

Monoclonal CRYM Antibody (monoclonal) (M09), Clone: 1C6
APR11690G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human CRYM (monoclonal) (M09). The antibodies are raised in mouse and are from clone 1C6. This antibody is applicable in WB, E

Monoclonal DLX1 Antibody (monoclonal) (M02), Clone: 3C7
APR11758G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human DLX1 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 3C7. This antibody is applicable in WB, E

Monoclonal GLI3 Antibody (monoclonal) (M01), Clone: 2C9
APR12034G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human GLI3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C9. This antibody is applicable in WB and IF, E

Monoclonal PLD2 Antibody (monoclonal) (M01), Clone: 1C5
APR07008G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PLD2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C5. This antibody is applicable in WB, E

Monoclonal ADD1 Antibody (monoclonal) (M01), Clone: 2C9
APR14818G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ADD1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C9. This antibody is applicable in WB and IHC, E

Monoclonal ARF7 Antibody (monoclonal) (M01), Clone: 2C8
APR14985G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ARF7 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2C8. This antibody is applicable in E

Monoclonal BVES Antibody (monoclonal) (M01), Clone: 1C3
APR15184G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human BVES (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1C3. This antibody is applicable in WB

Intercourse-based dimorphism of anticancer immune response and molecular mechanisms of immune evasion

Goal: We beforehand demonstrated that intercourse influences response tovimmune-checkpoint inhibitors. Right here we examine sex-based variations within the molecular mechanisms of anticancer immune-response and immune evasion in sufferers with NSCLC.
Experimental design: We analyzed a) transcriptome-data of 2575 early-stage NSCLCs from 7 totally different datasets; b) 327 tumor-samples extensively characterised on the molecular stage from the TRACERx lung examine; c) two impartial cohorts of respectively 329 and 391 sufferers with superior NSCLC handled with anti-PD1/anti-PDL1 medication.
Outcomes: As in contrast with males, the tumor microenvironment (TME) of ladies was considerably enriched for a lot of innate and adaptive immune cell-types, together with particular T-cell subpopulations. NSCLCs of women and men exploited totally different mechanisms of immune evasion.
The TME of females was characterised by considerably larger T-cell dysfunction standing, greater expression of inhibitory immune-checkpoint molecules and better abundance of immune-suppressive cells, together with Most cancers Related Fibroblasts, MDSCs and Regulatory T-cells. In contrast, the TME of males was considerably enriched for a T-cells excluded phenotype.
We reported information supporting impaired neoantigens presentation to immune system in tumors of males, as molecular mechanism explaining the findings noticed. Lastly, in step with our outcomes, we confirmed vital sex-based variations within the affiliation between TMB and end result of sufferers with superior NSCLC handled with anti-PD1/PDL1 medication.
Conclusions: We demonstrated significant sex-based variations of anticancer immune response and immune evasion mechanisms, which may be exploited to enhance immunotherapy efficacy for each ladies and men.

Serum high-molecular-weight adiponectin and response to dapagliflozin in sufferers with sort 2 diabetes and non-alcoholic fatty liver illness

A greater baseline renal operate is related to a greater response to sodium-glucose co-transporter-2 inhibitors in sufferers with sort 2 diabetes. Low serum adiponectin is related to visceral fats accumulation and hepatic steatosis.
  • We investigated the connection between baseline serum adiponectin and glycemic response to dapagliflozin in sufferers with sort 2 diabetes and non-alcoholic fatty liver illness (NAFLD). In a randomized, active-controlled, open-label trial, 57 sufferers with sort 2 diabetes and NAFLD had been randomized to both the dapagliflozin (5 mg/d) group or the management group.
  • Each teams had been handled for 24 weeks. Serum high-molecular-weight (HMW) adiponectin was measured with an ELISA equipment. Visceral fats space (VFA) was measured by twin bioelectrical impedance evaluation.
  • Hepatic steatosis was assessed by the managed attenuation parameter (CAP) measured by a transient elastography (FibroScan). Remedy with dapagliflozin considerably decreased HbA1c from 8.4%±1.5% at baseline to 7.4%±1.2% at 24 weeks. Each VFA and CAP decreased within the dapagliflozin group.
  • Baseline serum HMW adiponectin was negatively correlated with modifications in HbA1c from baseline to 24 weeks with dapagliflozin remedy. Within the multivariate evaluation, baseline HbA1c (β=-0.559, p=0.002) and serum HMW adiponectin (β=0.471, p=0.010) had been impartial determinants for the change (discount) in HbA1c.
  • Within the dapagliflozin group, the change in HbA1c was positively correlated with the modifications of CAP, however negatively correlated with the change in serum HMW adiponectin. In conclusion, a decrease serum stage of HMW adiponectin was related to a greater response to dapagliflozin in sufferers with sort 2 diabetes and NAFLD.Trial registration numberUMIN000022155.

 

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